Lời giải:
Gọi biểu thức là $P$
\(P=\frac{1-4}{4}.\frac{1-9}{9}...\frac{1-100}{100}=\frac{(1-2)(1+2)(1-3)(1+3)...(1-10)(1+10)}{2^2.3^2....10^2}\)
\(=\frac{(1-2)(1-3)...(1-10)}{2.3....10}.\frac{(1+2)(1+3)...(1+10)}{2.3.4...10}\)
\(=\frac{-1.2.3...9}{2.3...10}.\frac{3.4....11}{2.3.4..10}=\frac{-1}{10}.\frac{11}{2}=\frac{-11}{20}\)