\(P=xy\left(x+4\right)\left(y-2\right)+6x\left(x+4\right)+5y\left(y-2\right)+243\)
\(=y\left(y-2\right)\left[x\left(x+4\right)+5\right]+6\left[x\left(x+4\right)+5\right]+213\)
\(=y\left(y-2\right)\left(x^2+4x+5\right)+6\left(x^2+4x+5\right)+213\)
\(=\left(x^2+4x+5\right)\left(y^2-2y+6\right)+213\)
\(=\left[\left(x+2\right)^2+1\right].\left[\left(y-1\right)^2+5\right]+213\ge1.5+213=218\)
Dấu "=" xảy ra khi \(\hept{\begin{cases}x+2=0\\y-1=0\end{cases}}\Leftrightarrow\hept{\begin{cases}x=-2\\y=1\end{cases}}\)
Vậy \(P_{min}=218\Leftrightarrow\hept{\begin{cases}x=-2\\y=1\end{cases}}\)