Lời giải:
$4S=1.2.3(4-0)+2.3.4(5-1)+3.4.5(6-2)+...+k(k+1)(k+2)[(k+3)-(k-1)]$
$=[1.2.3.4+2.3.4.5+3.4.5.6+...k(k+1)(k+2)(k+3)]-[0.1.2.3+1.2.3.4+2.3.4.5+....+(k-1)k(k+1)(k+2)]$
$=k(k+1)(k+2)(k+3)$
$\Rightarrow 4S+1=k(k+1)(k+2)(k+3)+1=[k(k+3)][(k+1)(k+2)]+1$
$=(k^2+3k)(k^2+3k+2)+1=(k^2+3k)^2+2(k^2+3k)+1=(k^2+3k+1)^2$
$\Rightarrow 4S+1$ là số chính phương.