\(\left(x+1\right)\left(x+2\right)\left(x^2+4\right)\left(x-1\right)\left(x^2+1\right)\left(x-2\right)=\left(x+1\right)\left(x-1\right)\left(x+2\right)\left(x-2\right)\left(x^2+4\right)\left(x^2+1\right)\)
\(=\left(x^2-1\right)\left(x^2+1\right)\left(x^2+4\right)\left(x^2-4\right)=\left(x^4-1\right)\left(x^4-16\right)\)