\(\frac{2}{xy}:\left(\frac{1}{x}-\frac{1}{y}\right)^2-\frac{x^2+y^2}{\left(x-y\right)^2}\)
\(=\frac{2}{xy}:\left(\frac{y-x}{xy}\right)^2-\frac{x^2+y^2}{\left(x-y\right)^2}\)
\(=\frac{2}{xy}:\frac{\left(x-y\right)^2}{x^2y^2}-\frac{x^2+y^2}{\left(x-y\right)^2}\)
\(=\frac{2x^2y^2}{xy\left(x-y\right)^2}-\frac{x^2+y^2}{\left(x-y\right)^2}\)
\(=\frac{2xy}{\left(x-y\right)^2}-\frac{x^2+y^2}{\left(x-y\right)^2}=\frac{-x^2+2xy-y^2}{\left(x-y\right)^2}\)
\(=-\frac{\left(x-y\right)^2}{\left(x-y\right)^2}=-1\)