\(\left(-2\right)^3.\left(\frac{3}{4}-0,25\right):\left(2\frac{1}{4}-1\frac{1}{6}\right)\)
\(=\left(-8\right).\left(\frac{3}{4}-\frac{1}{4}\right):\left(\frac{9}{4}-\frac{7}{6}\right)\)
\(=\left(-8\right).\frac{1}{2}:\frac{13}{12}\)
\(=\left(-4\right).\frac{12}{13}\)
\(=\frac{-48}{13}\)