\(8\left(x+\frac{1}{x}\right)^2+4\left(x^2+\frac{1}{x^2}\right)^2-4\left(x^2+\frac{1}{x^2}\right)\left(x^2+\frac{1}{x^2}+2\right)=\left(x+4\right)^2\)
\(\Leftrightarrow8\left(x+\frac{1}{x}\right)^2-8\left(x^2+\frac{1}{x^2}\right)=\left(x+2\right)^2\)
\(\Leftrightarrow8\left(x^2+\frac{1}{x^2}+2\right)-8\left(x^2+\frac{1}{x^2}\right)=\left(x+2\right)^2\)
\(\Leftrightarrow\left(x+2\right)^2=16\)
\(\Rightarrow\left[{}\begin{matrix}x=2\\x=-6\end{matrix}\right.\)