\(D=\left(x-1\right)\left(x+2\right)\left(x+3\right)\left(x+6\right)\)
\(=\left[\left(x-1\right)\left(x+6\right)\right]\left[\left(x+2\right)\left(x+3\right)\right]\)
\(=\left(x^2+5x-6\right)\left(x^2+5x+6\right)\)
\(=\left(x^2+5x\right)^2-6x^2=\left(x^2+5x\right)^2-36\)
Vì \(\left(x^2+5x\right)^2\ge0\Rightarrow\left(x-1\right)\left(x+2\right)\left(x+3\right)\left(x+6\right)\ge-36\)
\("="\Leftrightarrow\left(x^2+5x\right)^2=0\Leftrightarrow\left[{}\begin{matrix}x=0\\x=-5\end{matrix}\right.\)