\(\left(x^2+22x+120\right)\left(x^2+33x+270\right)-2x^2\)
\(=\left(x+10\right)\left(x+12\right)\left(x+18\right)\left(x+15\right)-2x^2\)
\(=\left(x^2+28x+180\right)\left(x^2+27x+280\right)-2x^2\)
\(=\left(x^2+180\right)^2+55x\left(x^2+180\right)+754x^2\)
\(=\left(x^2+29x+180\right)\left(x^2+26x+180\right)\)
\(=\left(x+9\right)\left(x+20\right)\left(x^2+26x+180\right)\)