Ta có: \(\dfrac{1}{\left(x-1\right)\left(x-3\right)}+\dfrac{1}{\left(x-3\right)\left(x-5\right)}+\dfrac{1}{\left(x-5\right)\left(x-7\right)}=\dfrac{3}{16}\) \(\Rightarrow\dfrac{1}{2}\left(\dfrac{1}{x-1}-\dfrac{1}{x-3}+\dfrac{1}{x-3}-\dfrac{1}{x-5}+\dfrac{1}{x+5}-\dfrac{1}{x-7}\right)=\dfrac{3}{16}\)
\(\Rightarrow\) \(\dfrac{1}{2}\left(\dfrac{1}{x-1}-\dfrac{1}{x-7}\right)=\dfrac{3}{16}\)
\(\Rightarrow\) \(\dfrac{6}{x^2-8x+7}=\dfrac{3}{8}\)
\(\Rightarrow\) \(x^2-8x+7=16\)
\(\Rightarrow\) \(x^2-8x-9=0\)
\(\Rightarrow\) \(\left(x-9\right)\left(x+1\right)=0\)
\(\Rightarrow\) \(\left\{{}\begin{matrix}x=9\\x=-1\end{matrix}\right.\)
Vậy: Nghiệm lớn nhất của phương trình là: \(x=9\).