\(\left(x^2+6x+8\right)\left(x^2+14x+48\right)+16\)
\(=\left(x+2\right)\left(x+4\right)\left(x+6\right)\left(x+8\right)+16\)
\(=\left(x^2+10x+16\right)\left(x^2+10x+24\right)+16\)
\(=\left(x^2+10x\right)^2+40\left(x^2+10x\right)+400\)
\(=\left(x^2+10x+20\right)^2\)