`a)(2x-y)(4x^-2xy+y^2)`
`=(2x)^3-y^3`
`=8x^3-y^3`
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`b)(21x^2+67x-60)(x-5)`
`=x(21x^2+67x-60)-5(21x^2+67x-60)`
`=21x^3+67x^2-60x-105x^2-335x+300`
`=21x^3-38x^2-395x+300`
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`c)(2x^2+x-25)(x^2+5x-2)`
`=2x^2(x^2+5x-2)+x(x^2+5x-2)-25(x^2+5x-2)`
`=2x^4+10x^3-4x^2+x^3+10x^2-2x-25x^2-125x+50`
`=2x^4+11x^3-19x^2-127x+50`
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`d)(27x-8)(6x+9x^2+4)`
`=27x(6x+9x^2+4)-8(6x+9x^2+4)`
`=16x^2+243x^3+108x-48x-72x^2-32`
`=243x^3-56x^2+60x-32`