\(-1^2+2^2-3^2+4^2-5^2+6^2...-99^2+100^2\)
\(=100^2-99^2+...6^2-5^2+4^2-3^2+2^2-1^2\)
\(=\left(100-99\right)\left(100+99\right)+...+\left(6-5\right)\left(6+5\right)+\left(4-3\right)\left(4+3\right)+\left(2-1\right)\left(2+1\right)\)
\(=199+...+11+7+3\)
\(=\left(3+199\right).\left(\dfrac{199-3}{4}+1\right):2\)
\(=5050\)