\(3\left(4+1\right)\left(4^2+1\right)\left(4^4+1\right)\left(4^8+1\right)\left(4^{16}+1\right)\)
\(=\left(4-1\right)\left(4+1\right)\left(4^2+1\right)\left(4^4+1\right)\left(4^8+1\right)\left(4^{16}+1\right)\)
\(=\left(4^2-1\right)\left(4^2+1\right)\left(4^4+1\right)\left(4^8+1\right)\left(4^{16}+1\right)\)
\(=\left(4^4-1\right)\left(4^4+1\right)\left(4^8+1\right)\left(4^{16}+1\right)\)
\(=\left(4^8-1\right)\left(4^8+1\right)\left(4^{16}+1\right)\)
\(=\left(4^{16}-1\right)\left(4^{16}+1\right)\)
\(=4^{32}-1\)