\(\left(x+2\right)\left(x+4\right)\left(x+6\right)\left(x+8\right)+16\)
\(=\left(x+2\right)\left(x+8\right)\left(x+4\right)\left(x+6\right)+16\)
\(=\left(x^2+8x+2x+16\right)\left(x^2+6x+4x+24\right)+16\)
\(=\left(x^2+10x+16\right)\left(x^2+10x+24\right)+16\)
\(=\left(x^2+10x+16\right)\left(x^2+10+16+8\right)+16\)
\(=\left(x^2+10x+16\right)^2+2.\left(x^2+10x+16\right).4+4^2\)
\(=\left(x^2+10x+16+4\right)^2\)
\(=\left(x^2+10+20\right)^2\)
\(\left(x+2\right)\left(x+4\right)\left(x+6\right)\left(x+8\right)+16\)
\(=\left[\left(x+2\right)\left(x+8\right)\right]\left[\left(x+4\right)\left(x+6\right)\right]+16\)
\(=\left(x^2+8x+2x+16\right)
\left(x^2+6x+4x+24\right)+16\)
\(=\left(x^2+10x+16\right)\left(x^2+10x+24\right)+16\left(1\right)\)
\(\text{Đặt }x^2+10x+\frac{16+24}{2}=t\)
\(\text{hay }x^2+10x+20=t\)
\(\left(1\right)\Rightarrow\left(t-4\right)\left(t+4\right)+16\)
\(=t^2-4^2+16\)
\(=t^2-16+16\)
\(=t^2\)
\(=\left(x^2+10x+20\right)^2\)