Đặt \(x+6=a\) phương trình trở thành
\(\left(a-1\right)^4+\left(a+1\right)^4=80\)
\(\Leftrightarrow a^4-4a^3+6a^2-4a+1+a^4+4a^3+6a^2+4a+1=80\)
\(\Leftrightarrow2a^4+12a^2+2=80\)
\(\Leftrightarrow a^4+6a^2-39=0\)
\(\Rightarrow a^2=-3+4\sqrt{3}\Rightarrow a=\pm\sqrt{-3+4\sqrt{3}}\)
\(\Rightarrow x=-6\pm\sqrt{-3+4\sqrt{3}}\)