\(\dfrac{8^5\cdot\left(-5\right)^8+\left(-2\right)^5\cdot10^9}{2^{16}\cdot5^7+20^8}\)
\(=\dfrac{2^{15}\cdot5^8-2^{14}\cdot5^9}{2^{16}\cdot5^7+2^{16}\cdot5^8}\)
\(=\dfrac{2^{14}\cdot5^8\left(2-5\right)}{2^{16}\cdot5^7\cdot\left(1+5\right)}\)
\(=\dfrac{5\cdot\left(-3\right)}{4\cdot6}=\dfrac{-15}{24}=\dfrac{-5}{8}\)