\(E=\dfrac{4^5.9^4-2.6^9}{2^{10}.3^8+6^8.20}=\dfrac{\left(2^2\right)^5.\left(3^2\right)^4-2.\left(2.3\right)^9}{2^{10}.3^8+\left(2.3\right)^8.2^2.5}\)
\(=\dfrac{2^{10}.3^8-2^{10}.3^9}{2^{10}.3^8+2^{10}.3^8.5}=\dfrac{2^{10}.3^8\left(1-3\right)}{2^{10}.3^8\left(1+5\right)}=\dfrac{-2}{6}=-\dfrac{1}{3}\)